“Although most autoimmune diseases are considered to be CD4 T cell- or antibody-mediated, many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma cells. This includes…
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“The coronavirus disease 2019 (COVID-19) pandemic is concerning for patients with neuroimmunological diseases who are receiving immunotherapy. Uncertainty remains about whether immunotherapies…
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“Cerebrospinal fluid (CSF) is a vital liquid, providing nutrients and signaling molecules and clearing out toxic by-products from the brain. The CSF is produced by the choroid plexus (ChP), a…
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Oggi più che mai, per far fronte a questa emergenza, continuiamo a sostenere la ricerca sulla SM, anche con progetti dedicati alla comprensione dei rapporti tra COVID 19 e SM. È con piacere che Le…
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“Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions in pathology is complicated by changes…
Read moreAbstract Epigenetic modifications on DNA and histones regulate gene expression by modulating chromatin accessibility to transcription machinery. Here we identify methionine as a key nutrient affecting…
Read moreA recent review that addressed, through meta-analysis of pusblished data, the safety and efficacy of autologous mesenchymal stem cells (aMSCs) in treating MS patients. Source: Hindawi, Stem Cells International
Read moreKetone bodies are produced during pathological (e.g. untreated diabetes) or paraphysiological (starvation or prolonged exercise) states as an alternative metabolic fuel for muscles, heart and brain….
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The revelation on Monday that health-care workers have been infected by the virus that seemingly started spreading from fish market in Wuhan, China, considered a litmus test for a pathogen’s ability…
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A survey of more than 4,000 scientists has painted a damning picture of the culture in which they work, suggesting that highly competitive and often hostile environments are damaging the quality of…
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