“Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions in pathology is complicated by changes to the macrophage phenotype during inflammation. Here…
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Abstract Epigenetic modifications on DNA and histones regulate gene expression by modulating chromatin accessibility to transcription machinery. Here we identify methionine as a key nutrient affecting epigenetic reprogramming in CD4 + T helper (Th)…
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A recent review that addressed, through meta-analysis of pusblished data, the safety and efficacy of autologous mesenchymal stem cells (aMSCs) in treating MS patients. Source: Hindawi, Stem Cells International
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Ketone bodies are produced during pathological (e.g. untreated diabetes) or paraphysiological (starvation or prolonged exercise) states as an alternative metabolic fuel for muscles, heart and brain. Ketogenic diets, which are characterized by high fatty acid…
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