Inhibition of amyloid-β plaque formation by α-synucleinBachhuber et al. Nature Medicine – July 2015 Amyloid-β (Aβ) plaques and α-synuclein (α-syn)-rich Lewy bodies are the major neuropathological hallmarks of Alzheimer’s…
Read moreAntibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathyKondo et al. Nature – July 2015 Traumatic brain injury (TBI), characterized by acute neurological dysfunction, is one of the best known environmental risk factors…
Read moreshRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease modelZharikov et al. The Journal of Clinical Investigation – July 2015 Multiple convergent lines of evidence implicate both α-synuclein (encoded by SCNA)…
Read moreHyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivoShannon L. Macauley et al. jci.org – June 2015 Epidemiological studies show that patients with type 2 diabetes (T2DM) and individuals with a diabetes-independent…
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