Oct 18, 2018 Last Updated 12:11 PM, Oct 16, 2018

Cancer immunologists scoop medicine Nobel prize

Published in Head news
Read 87 times
Rate this item
(0 votes)

 

Two days ago, a monday no less, James P Allison and Tasuku Honjo have been abruptly awaken (by their colleagues and relatives, before the Royal Swedish Academy of Sciences, it would seem) by the greatest new that a scientist could possibly believe to receive on a random day of his or her life:  they had been awarded with the 2018 Nobel Prize for physiology or medicine.

 

Allison and Honjo worked in the '90s, on the immunoregulative proteins PD-1 and CTLA-4 and were pioneers of cancer immunotherapy, as they searched a way to exploit these two proteins in order to remove the brakes that tumours to put on T cells in order to suppress their oncosuppressive, immune attack. Drugs and antibody that target CTLA-4 and PD-1 represent today pivotal milestones of cancer therapy and are used today to treat several tumours.

Quite importantly, this award demonstrates how good basic research embodies one of the most important substrates on which clinical solutions can rise.    

Nature News

Last modified on Wednesday, 03 October 2018 13:24
Login to post comments

Registered area

Thanks to the support of
merck serono biogen sanofi

Conferences & Courses

17° Corso CRNI Viva la differenza: sesso e neuroimmunologia

March 7-10, 2018 
Bergamo - Bergamo Science Center

READ MORE

Encefaliti Autoimmuni e Malattie Demielinizzanti Atipiche

16 febbraio 2018
Aula Magna Giorgio De Sandre
POLICLINICO UNIVERSITARIO G.B. ROSSI - Verona

READ MORE

JNIInternational Brain Research Organization
Bringing Neuroscience to the World
JNIJournal of Neuroimmunology
Studies on all branches of neurosciences covering both research and clinical problems of neuroscientific interest.

This website or its third party tools use cookies, which are necessary to its functioning and required to achieve the purposes illustrated in the cookie policy. If you want to know more or withdraw your consent to all or some of the cookies, please refer to the cookie policy. By closing this banner, scrolling this page, clicking a link or continuing to browse otherwise, you agree to the use of cookies. To find out more about the cookies we use and how to delete them, see our Cookie Policy