Nov 22, 2017 Last Updated 4:46 PM, Nov 21, 2017

Methotrexate has no steroid-sparing effect in patients with generalized myasthenia gravis

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Myasthenia gravis (MG) is a chronic autoimmune disease characterized by fluctuating muscle weakness, which, in the majority of patients, is treated with corticosteroids. In a recently published clinical trial, 50 patients with generalized MG were randomly assigned to prednisone + methotrexate or prednisone + placebo. The amount of prednisone that…

Nature Reviews Neurology; June 2016

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